Serum is the fluid component of blood, refined to eliminate clotting factors, white blood cells, red blood cells, and platelets. Fetal Bovine Serum (FBS) is harvested from the fetuses of pregnant cattle during slaughter that have been deemed fit for human consumption by a veterinarian through ante-mortem and post-mortem inspection. After initial collection, FBS is refined to remove:
- antibodies
- antigens
- electrolytes
- fibrinogens
- foreign substances (drugs or microorganisms, for example)
- hormones
- platelets
- red blood cells
- white blood cells
Thus, Fetal Bovine Serum could be defined as blood plasma without clotting factors.
The final Fetal Bovine Serum (FBS) product is a yellow-colored which is rich in proteins, nutrients, and growth factors while having lower levels of antibodies. Bovine Serum Albumin (BSA) is the largest component of FBS.
Fetal Bovine Serum may be sourced from the USA or imported in accordance with USDA regulations.